Sugar acids and derivatives
Sigma Aldrich Fine Chemicals Biosciences Sialic Acid Quantitation K
The Sialic Acid Quantitation Kit provides a rapid and accurate determination of total N-acetylneuraminic acid (NANA sialic acid). NANA is released from glycoconjugates using neuraminidase. The kit uses alpha(2-3 6 8 9) neuraminidase to cleave all NANA linkages including alpha(2-8) and alpha(2-9) linkages as well as branched NANA for the most accurate determination of total sialic acid content.
![eMolecules 3-AZABICYCLO[3.1.0]HEXANE-1-CARBONITRILE HBR | 2007919-32-4 | MFCD30471580 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183316.JPG-250.jpg)
eMolecules 3-AZABICYCLO[3.1.0]HEXANE-1-CARBONITRILE HBR | 2007919-32-4 | MFCD30471580 | 1g
AstaTech | 3-AZABICYCLO[3.1.0]HEXANE-1-CARBONITRILE HBR | 1g | 290683369 | P14880 | 95.000 | 2007919-32-4 | MFCD30471580 | 189.056 | C6H9BrN2
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Medchemexpress LLC D-α-hydroxyglutaric acid disodium | 103404-90-6 | MFCD00069573 | >95.0% | 192.08 | C5H6Na2O5 | 25 MG
D-α-hydroxyglutaric acid disodium is the disodium salt of the R-enantiomer of 2-hydroxyglutarate, provided as a research reagent for biochemical and analytical studies. It is the principal metabolite in D-2-hydroxyglutaric aciduria and acts as a weak competitive antagonist of α-ketoglutarate, affecting α-KG-dependent dioxygenases. Molecular formula C5H6Na2O5; molecular weight 192.08; store at 4°C, sealed and away from moisture.
- Disodium salt form for improved solubility and handling.
- R-enantiomer specificity for enantioselective biological studies.
- Inhibits α-KG-dependent dioxygenases for mechanistic assays.
- Useful for biochemical, metabolic, and analytical research applications.
- Known molecular formula and molecular weight for formulation and dosing calculations.
- Stable when stored sealed at 4°C away from moisture.
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
Medchemexpress LLC Diethylstilbestrol-d8 | 91318-10-4 | MFCD01074086 | 99.7% | C18H12D8O2 | 10MG
Diethylstilbestrol-d8 is the deuterium-labeled analogue of diethylstilbestrol supplied as a high-purity powder for research and analytical use. It is intended as a stable isotope internal standard for LC-MS, pharmacokinetic studies, and quantitative assays where mass differentiation from the parent compound is required.
- High isotopic purity suitable for mass spectrometry internal standard.
- Purity 99.7% as supplied.
- Molecular formula C18H12D8O2 and molecular weight 276.40.
- Recommended solvent: DMSO, 50 mg/mL with ultrasonic and warming.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Supplied in small research pack sizes appropriate for analytical workflows.
Cayman Chemical Febuxostat Acyl GlucuronID 1mg
A metabolite of febuxostat; is formed via glucuronidation of febuxostat by UGTs
Medchemexpress LLC 2-(4-heptylphenethyl)-6-hydroxybenzoic acid | 1243583-85-8 | MFCD22123243 | 99.6% | 340.46 g/mol | C22H28O3 | 10 MG
MG 149 is a small-molecule inhibitor of Tip60 (histone acetyltransferase) used in preclinical research to probe acetyltransferase activity and related mitochondrial pathways. It shows activity versus MOF/KAT8 and can influence PINK1-dependent mitochondrial clearance; supplied as a white to off-white solid with high analytical purity for laboratory use.
- Tip60 (HAT) inhibitor with reported IC50 ≈ 74 μM for Tip60 and ≈ 47 μM for MOF.
- High purity (HPLC 99.6%).
- Chemical formula C22H28O3; molecular weight 340.46 g/mol.
- White to off-white solid suitable for bench-scale research.
- Storage: powder at -20°C (stable 3 years) or 4°C (stable 2 years); in solvent at -80°C (2 years) or -20°C (1 year).
- Common applications: epigenetics assays, acetyltransferase inhibition studies, and mitochondrial/PINK1 pathway research.